Circulating Human Neonatal Naïve B Cells are Deficient in CD73 Impairing Purine Salvage
نویسندگان
چکیده
منابع مشابه
Circulating Human Neonatal Naïve B Cells are Deficient in CD73 Impairing Purine Salvage
BACKGROUND Extracellular purines, in particular adenosine (Ado) and adenosine-triphosphate, are critical immunoregulatory molecules. Expression and activity of purine ecto-enzymes on B cells in neonatal and adult blood may influence their function and has been incompletely characterized. METHODS Mononuclear cells were isolated from human neonatal (cord blood) or adult (peripheral blood) subje...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2016
ISSN: 1664-3224
DOI: 10.3389/fimmu.2016.00121